Israel Grilo-Bensusan *

Autor invitado por SIIC

Este estudio aclara la indicación de la gammagrafía con macroagregados de albúmina en el diagnóstico y pronóstico del síndrome hepatopulmonar.

UTILIDAD DE LA GAMMAGRAFÍA CON MACROAGREGADOS DE ALBÚMINA EN EL SÍNDROME HEPATOPULMONAR

La gammagrafía con macroagregados de albúmina tiene baja sensibilidad para el diagnóstico del síndrome hepatopulmonar. Puede ser útil en caso de enfermedad pulmonar concomitante. Sus valores no se correlacionan con la mortalidad en los casos leves o moderados y se normalizan tempranamente luego del trasplante hepático.

*Israel Grilo-Bensusan
describe para SIIC los aspectos relevantes de su trabajo
THE UTILITY OF THE MACRO-AGGREGATED ALBUMIN LUNG PERFUSION SCAN IN THE DIAGNOSIS AND PROGNOSIS OF HEPATOPULMONARY SYNDROME
Institución principal de la investigación
*Hospital de Alta Resolución de Écija. Agencia Pública Sanitaria Bajo Guadalquivir., Écija, España
Imprimir nota

Comprar este artículo
Otros artículos escogidos

Referencias bibliográficas
1. Rodríguez Roisin R, Krowka MJ, Herve P, et al; ERS Task Force Pulmonary-Hepatic Vascular Disorders (PHD) Scientific Committee. Pulmonary-Hepatic vascular disorders (PHD). Eur Respir J 24:861-880, 2004.
2. Rodríguez Roisin R, Krowka MJ. Hepatopulmonary syndrome. A liver-induced lung vascular disorder. N Engl J Med 358:2378-87, 2008.
3. Aller R, Moya JL, Moreira V et al. Diagnosis of hepatopulmonary syndrome with contrast transesophageal echocariography. Advantages over contrast transthoracic echocardiography. Dig Dis Sci 44:1243-1248, 1999.
4. Abrams GA, Jaffe CC, Hoffer PB, et al. Diagnostic utility of contrast echocardiography and lung perfusion scan in patients with hepatopulmonary syndrome. Gastroenterology 109:1283-1288, 1995.
5. Abrams GA, Nanda NC, Dubovsky EV, et al. Use of macroaggregated albuming lung perfusion scan to diagnose hepatopulmonary syndrome: a new approach. Gastroenterology 114:305-310, 1998.
6. Krowka MJ, Wiseman GA, Burnett OL, et al. Hepatopulmonary syndrome: a prospective study of relationships between severity of liver disease, PaO(2) response to 100% oxygen, and brain uptake after (99m)Tc MAA lung scanning. Chest 118:615-624, 2000.
7. Arguedas MR, Abrams GA, Krowka MJ, et al. Prospective evaluation of outcomes and predictors of mortality in patients with hepatopulmonary syndrome undergoing liver transplantation. Hepatology 37:192-197, 2003.
8. Swanson KL, Wiesner RH, Krowka MJ. Natural history of hepatopulmonary syndrome: Impact of liver transplantation. Hepatology 41:1122-1129, 2005.
9. Márquez E, Jara L, Ortega F, et al. Síndrome hepatopulmonar en paciente con hepatopatía avanzada: estudio de 24 casos. Med Clin (Barc) 130:98-102, 2008.
10. Rodríguez Roisin R, Roca J. Hepatopulmonary syndrome: the paradigm of liver-induced hypoxaemia. Baillieres Clin Gastroenterol 11:387-406, 1997.
11. Krowka MJ. Hepatopulmonary syndrome: recent literature (1997 to 1999) and implications for liver transplantation. Liver Transpl 6:S31-S35, 2000.
12. Kim HY, Choi MS, Lee SC, et al. Outcomes in patients with hepatopulmonary syndrome undergoing liver transplantation. Transpl Proc 36:2762-2763, 2004.
13. Deberaldini M, Arcanjo ABB, Melo E, et al. Hepatopulmonary syndrome: morbidity and survival after liver transplantation. Transpl Proc 40:3512-3516, 2008.
14. Gupta S, Castel H, Rao RV et al. Improved survival after liver transplantation in patients with hepatopulmonary syndrome. Am J Transplant 9:1-10, 2009.
15. Martínez Palli G, Gómez FP, Barberá JA, et al. Sustained low diffusing capacity in hepatopulmonary syndrome after liver transplantation. World J Gastroenterol 12:5878-5883, 2006.
16. Pascasio JM, Grilo I, López Pardo FJ, et al. Prevalence and severity of hepatopulmonary syndrome and its influence on survival in cirrhotic patients evaluated for liver trasplantation. Am J Transplant 14:1391-1399, 2014.
17. Chiang St. A nomogran for venous shunt calculation. Thorax 23:536-5, 1968.
18. Krowka MJ, Mandell MS, Ramsay MA et al. Hepatopulmonary syndrome and portopulmonary hypertension: a report of the multicenter liver transplant database. Liver Transpl 10:174-182, 2004.
19. Taille C, Cadranel J, Bellocq A, et al. Liver transplantation for hepatopulmonary syndrome: a ten-year experience in Paris, France. Transplantation 75:1482-1489, 2003.
20. Whyte MK, Hughes JM, Peters AM, et al. Analysis of intrapulmonary right to left shunt in the hepatopulmonary syndrome. J Hepatol 29:85-93, 1998.
21. Aller R, Moya JL, Moreira V, et al. Diagnosis and grading of intrapulmonary vascular dilatation in cirrhotic patients with contrast transesophageal echocardiography. J Hepatol 31:1044-1052, 1999.
22. Schenk P, Fuhrmann V, Madl C, et al. Hepatopulmonary syndrome: prevalence and predictive value of various cut offs for arterial oxygenation and their clinical consequences. Gut 51:853-859, 2002.
23. Lima BL, França AV, Pazin Filho A, et al. Frequency, clinical characteristics, and respiratory parameters of hepatopulmonary syndrome. Mayo Clin Proc 79:42-48, 2004.
24. Iyer VN, Swanson KL, Cartin-Ceba R, et al. Hepatopulmonary syndrome: favorable outcomes in the MELDexception era. Hepatology 57:2427-2435, 2013.

Otros artículos de Israel Grilo-Bensusan

Pascasio JM, Grilo I, López Pardo FJ, Ortega Ruiz F, Tirado JL, Sousa JM, Rodríguez Puras MJ, Ferrer MT, Sayago M, Gómez Bravo MA, Grilo A. Prevalence and severity of hepatopulmonary syndrome and its influence on survival in cirrhotic patients evaluated for liver transplantation. Am J Transplant 14(6):1391-9, 2014. doi: 10.1111/ajt.12713. Epub 2014 Apr 14. PubMed PMID: 24730359.
Grilo Bensusan I, Pascasio Acevedo JM. Hepatopulmonary syndrome: What we know and what we would like to know. World J Gastroenterol 22(25):5728-41, 2016. doi: 10.3748/wjg.v22.i25.5728.
Márquez Martín E, Jara Palomares L, Ortega Ruiz F, Grilo Bensusán I,
López Campos JL, Cejudo Ramos P, Pascasio JM, Rodríguez Becerra E. Hepatopulmonary syndrome in patients with advanced hepatic disease: study of a series of 24 cases. Med Clin (Barc). 130(3):98-102, 2008.
Grilo Bensusan I, Pascasio Acevedo JM. Hepatopulmonar syndrome. Rev Esp Enferm Dig 105(6):366, 2013.
Pineda JA, García García JA, Aguilar Guisado M, Ríos Villegas MJ, Ruiz Morales J, Rivero A, Del Valle J, Luque R, Rodríguez Baño J, González Serrano M, Camacho A, Macías J, Grilo I, Gómez Mateos JM; Grupo para el Estudio de las Hepatitis Víricas de la Sociedad Andaluza de Enfermedades Infecciosas (SAEI). Clinical progression of hepatitis C virus-related chronic liver disease in human immunodeficiency virus-infected patients undergoing highly active antiretroviral therapy. Hepatology 46(3):622-30, 2007.
García García JA, Romero Gómez M, Girón González JA, Rivera Irigoin R, Torre Cisneros J, Montero JL, González Serrano M, Andrade RJ, Aguilar Guisado M, Grilo I, Martín Vivaldi J, Salmerón J, Caballero Granado FJ, Macías J, Vergara López S, Pineda JA; Grupo Andaluz para el Estudio de las Enfermedades Infecciosas (GAEI); Grupo Andaluz para el Estudio del Hígado (GAEH). Incidence of and factors associated with hepatocellular carcinoma among hepatitis C virus and
human immunodeficiency virus coinfected patients with decompensated cirrhosis. AIDS Res Hum Retroviruses 22(12):1236-41, 2006.
Grilo Bensusan I, Herrera Martín P, Aguado Álvarez MV. Prospective study of anxiety in patients undergoing an outpatient colonoscopy. Rev Esp Enferm Dig 108(12):765-769, 2016.
Grilo I, Torres Gómez J, Gómez Regife L. Atypical melanosis coli resembling the appearance of cheetah skin. Endoscopy 46 Suppl 1, 2014. UCTN:E437-8. Doi: 10.1055/s-0034-1377427.
Grilo Bensusan I, Gómez Regife L. Primary syphilitic chancre in the rectum. Endoscopy 46 Suppl 1, 2014. UCTN:E533. doi: 10.1055/s-0034-1377638.
Grilo Bensusan I, Gómez Delgado E, Gómez Regife L. Melatonin as a probable cause of diarrhoea. Rev Esp Enferm Dig 107(2):119-20, 2015.

Para comunicarse con Israel Grilo-Bensusan mencionar a SIIC como referencia:
igrilob@telefonica.net

---

Acerca del trabajo completo

UTILIDAD DE LA GAMMAGRAFÍA CON MACROAGREGADOS DE ALBÚMINA EN EL SÍNDROME HEPATOPULMONAR

Título original en castellano
UTILIDAD DE LA GAMMAGRAFIA DE PERFUSION CON MACROAGREGADOS DE ALBUMINA EN EL DIAGNOSTICO Y PRONOSTICO DEL SINDROME HEPATOPATOPULMONAR EN CANDIDATOS A TRASPLANTE HEPATICO

Autor

ua40317