Carlo Godoy Olivares *

Autor invitado por SIIC

Este estudio fue llevado a cabo en cerdos clínicamente enfermos y la administración del fármaco fue realizada bajo condiciones habituales de uso en el sistema productivo (ad libitum)

INFLUENCIA DE UNA ENFERMEDAD RESPIRATORIA EN LA FARMACOCINÉTICA DE AMOXICILINA EN CERDOS

Las propiedades farmacocinéticas y la disposición de amoxicilina en los tejidos del aparato respiratorio puede ser influenciada por el estado de enfermedad o por factores relacionados tales como cambios en el tránsito gastrointestinal. Estas variaciones en el comportamiento farmacocinético deberían ser consideradas para la selección de un régimen de dosificación óptimo que garantice la eficacia terapéutica.

*Carlo Godoy Olivares
describe para SIIC los aspectos relevantes de su trabajo
INFLUENCE OF A PIG RESPIRATORY DISEASE ON THE PHARMACOKINETIC BEHAVIOUR OF AMOXICILLIN AFTER ORAL AD LIBITUM ADMINISTRATION IN MEDICATED FEED
Institución principal de la investigación
*Servei D’anàlisi de Fàrmacs Departament de Farmacologia, de Terapèutica I de Toxicologia Facultat Veterinaria Universitat Autònoma de Barcelona, Barcelona, España
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Pérez R. I. Cabezas, C. Godoy, L. Rubilar, L. Días, L. Muñoz. M. Arboix, M. Alvinerie. 2001. Disposición plasmática y fecal de moxidectina administrada por vía oral en caballos. Archivos de Medicina Veterinaria, 33: 77-88.

Pérez, R., I Cabezas, C. Godoy, L. Rubilar, L. Muñoz M. Arboix, G. Castells, M. Alvinerie. 2002. Pharmacokinetics of doramectin and ivermectin after oral administration in horses. The Veterinary Journal, 163: 161-167.

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Capece, BPS, S. Afonso, M. Harun, C. Godoy, G. Castells, C. Cristofol. 2009. Effect of age and gender in the pharmacokinetics of albendazole and albendazole sulphoxide enantiomers in goats. Research in Veterinary Science, 86: 498-502.

Godoy, C., G. Castells, G. Martí, B. Capece, F. Pérez, H. Colom, C. Cristofol. 2010. Influence of a pig respiratory disease on the pharmacokinetic behaviour of amoxicillin after oral ad libitum administration in medicated feed. J. Vet. Pharmacol. Therap.

Pérez, R., C. Godoy, C. Palma, L. Muñoz, M. Arboix, M. Alvinerie. 2010. Plasma disposition and fecal elimination of doramectin after oral or intramuscular administration in horses. Veterinary Parasitology 170: 112–119.

Para comunicarse con Carlo Godoy Olivares mencionar a SIIC como referencia:
carlo.godoy@aub.es

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Acerca del trabajo completo

INFLUENCIA DE UNA ENFERMEDAD RESPIRATORIA EN LA FARMACOCINÉTICA DE AMOXICILINA EN CERDOS

Título original en castellano
INFLUENCIA DE UNA ENFERMEDAD RESPIRATORIA EN EL COMPORTAMIENTO FARMACOCINETICO DE AMOXICILINA DESPUES DE SU ADMINISTRACION ORAL AD LIBITUM EN PIENSO MEDICADO

Autores
Carlo Godoy Olivares¹, Glòria Castells Carles², Bettencourt P.s. Capece³, Francisco Pérez⁴, Gabriel Martí⁵, Helena Colom⁶, Carles Cristòfol⁷
1 Médico Veterinario, Servei D’anàlisi de Fàrmacs Departament de Farmacologia, de Terapèutica I de Toxicologia Facultat Veterinaria Universitat Autònoma de Barcelona, Barcelona, España, Veterinario
2 Investigadora, Servei D’anàlisi de Fàrmacs Departament de Farmacologia, de Terapèutica I de Toxicologia Facultat Veterinaria Universitat Autònoma de Barcelona, Responsable de Proyectos
3 Médico Veterinario, Secção de Farm e Tox, Dep Para-clínicas, Fac. de Veterinária, Univ. Eduardo Mondlane, Av.moçambique, Km 1,5. Maputo, Mozambique, Profesor
4 Experimentador, Seguridad y Bienestar Animal S.l. Can Pericas de Marata. Les Franqueses del Vallès, Barcelona, España., Experimentador
5 Veterinario, Laboratorio Jaer S.a. 08620 St. Vicenc¸ Dels Horts, Barcelona, España, Director Técnico
6 Profesora, Unitat de Biofarmàcia I Farmacocinètica. Facultat de Farmàcia. Univ. de Barcelona. Av.joan Xxiii,sn 08028 Barcelona,españa, Profesora Titular de Universidad y Direc
7 Farmacéutico, Servei D’anàlisi de Fàrmacs Departament de Farmacologia, de Terapèutica I de Toxicologia Facultat Veterinaria Universitat Autònoma de Barcelona, Director del Servei D’anàlisi de Fàrmacs

Acceso a la fuente original
Journal of Veterinary Pharmacology and Therapeutics
http://www.blackwellpublishing.com/journal.asp?ref=0140-7783&site=1

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