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Prachi Atram describes for SIIC the most significant aspects of his article describe para SIIC los aspectos relevantes de su artículo GINGIVAL CREVICULAR FLUID : A DIAGNOSTIC TOOL IN HIV Gingival crevicular fluid: a diagnostic marker in HIV positive patients ELISA is the most commonly used test for screening HIV patients. Generally it is found that people are scared of pricking injections, reluctant to give blood sample (quantity), think about cost effectiveness and also causes disturbances their social life. In the present era investigators are searching for alternative to serological testing. Recently it is proved that oral fluids testing can be used as an alternative to blood testing. New investigational devices are introduced like Orasure and others which collects the oral saliva, oral mucosal transudate. In the present study we used calibrated 5 µl disposable microcapillaries so that the uncontaminated gingival crevicular fluid (GCF) is obtained. According to Goodson the IgG content of GCF in periodontal pocket is approximately 100 times more than found in saliva and is now widely appreciated that GCF is formed as blood ultrafiltrate. In this study we studied many parameters and reached to the conclusion that GCF can also be of choice instead of serum because of non-invasivensess, painless, low cost effective, less sample, easy collection, safer disposal and better for clinicians because of patients better compliance. The above findings suggestive of GCF being better alternative and better diagnostic medium than serum and saliva so it can be used for detection of HIV. The article was published by El artículo fue publicado por
Principal institution where the research took place Institución principal de la investigación DEPARTMENT OF ORAL & MAXILLOFACIAL PATHOLOGY, GOVERNMENT DENTAL COLLEGE AND HOSPITAL ,NAGPUR., NAGPUR, MAHARASHTRA, India  Authors' Report Crónica del Autor Bibliographic references Referencias bibliográficas 1. Soto Ramírez LE, Hernández Gómez L, Sifuentes Osornio J, Barriga Angulo G, Duarte de Lima D, López Portillo M, et al. Detection of specific antibodies in gingival crevicular transudate by ELISA for diagnosis of HIV type1 infection. J Clin Microbiol 30:2780-3, 1992. 2. Reichart PA, Gelderblom HR, Becker J, Kuntz A. AIDS and the oral cavity. The HIV-infection: Virology, etiology, origin, immunology, precautions and clinical observation in 110 patients. Int J Oral Maxillofac Surg 16:129-53, 1987. 3. Balasundaram S. HIV Antibody Screening: Saliva as Alternative to Serum. Chennai, India: Ragas Dental College, 2002. 4. Mandel ID. Salivary diagnosis: More than a lick and a promise. J Am Dent Assoc 124:20-1, 1993. 5. Constantine N. HIV antibody assay: HIV in site, knowledge based chapter. United States: University of Maryland School of Medicine, 2006. 6. Jackson MM, Lynch P. The epidemiology of HIV infection, AIDS, and health care worker risk issues. Fam Community Health 12:34-42, 1989. 7. Goodson JM. Gingival crevice fluid flow. Periodontol 2000. 31:43-54, 2003. SIIC System of Assisted Editing (SSEA) / Sistema SIIC de Edición Asistida (SSEA)
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Information about the full text Acerca del trabajo completo Gingival Crevicular Fluid: As a Diagnostic Marker in HIV Positive Patients Author / Autor Prachi Atram1, Pallavi Patil2, Fatema Saify3, Vanita Rathod4, Swati Gotmore5, Pallavi Patil6, Fatema Saify7, Vanita Rathod8, Swati Gotmore9, Pallavi Patil10, Fatema Saify11, Vanita Rathod12, Swati Gotmore13, Pallavi Patil14, Fatema Saify15, Vanita Rathod16, Swati Gotmore17, Pallavi Patil18, Fatema Saify19, Vanita Rathod20, Swati Gotmore21 21 Proffessor, Department Of Oral Pathology, D.y.patil University ,school Of Dentistry,navi Mumbai, Maharashtra, India., Fifth Access to the original source Journal of International Society of Preventive and Community Dentistry siic DB: / siic DB: http://www.siicsalud.com/main/distriprinrel.php |
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