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Chakrakodi Shastry describes for SIIC the most significant aspects of his article describe para SIIC los aspectos relevantes de su artículo Identifying hepatotoxic effect of aripiprazole co-prescribed with carbamazepine and fluvoxamine EFFECT OF ARIPIPRAZOLE WITH CARBAMAZEPINE AND FLUVOXAMINE ON LIVER FUNCTION Aripiprazole given in combination with fluvoxamine, there was significant hepatotoxicity possibly due to inhibition of aripiprazole metabolizing enzyme CYP3A4. Similarly co-administration of carbamazepine, a CYP3A4 inducer may lead to significant decrease in plasma concentration of aripiprazole and potentially a loss in aripiprazole's clinical efficacy. The article was published by El artículo fue publicado por
Principal institution where the research took place Institución principal de la investigación NGSM Institute of Pharmaceutical Sciences, Mangalore, Karnataka, India  Authors' Report Crónica del Autor Bibliographic references Referencias bibliográficas Citrome L, Macher JP, Salazar DE, Mallikaardjun S, Boulton DW. Pharmacokinetics of aripiprazole and concomitant carbamacepine. J Clin Psychopharmacol 27(3):279-283, 2007. Dumortier G, Cabaret W, Stamatiadis L. Hepatic tolerance of atypical antipsychotic drugs. Encephale 28(6):542-551, 2002. Dumortier G, Cabaret W, Stamatiadis L. Hepatic tolerance of atypical antipsychotic drugs. Encephale 28(6):542-551, 2002. Ghosh MN. Fundamentals of experimental pharmacology. 4th ed. Kolkata: Hilton and company; 2008. Pp. 178. McLean EK, McLean AEM, Sutton PM. An improved method for producing cirrhosis of the liver in rats by stimulus administration of carbon tetrachloride and pentobarbitone. Brt J Exp Path 50:502-503, 1969. Michalets EL. Update: clinically significant cytochrome P-450 drug interactions. Pharmacotherapy 18(1):84-112, 1998. Olesen OV, Linnet K. Fluvoxamine-clozapine drug interaction: inhibition in vitro of five cytochrome P450 isoforms involved in clozapine metabolism. J Clin Psychopharmacol 20(1):35-42, 2000. Sharif ZA. Pharmacokinetics, metabolism and drug-drug interactions of atypical antipsychotics in special populations. Primary Care Companion J Clin Psychiatry 5(6):22-25, 2003. Other articles written by the author Chakrakodi Shastry Otros artículos de Chakrakodi Shastry Antivenom activity of ethanolic extract of Crescentia cujete fruit. Shastry C.S., Aswathanarayana B.J., Bhalodia Maulik. Int.J.Phytomed., 4(1), 2012. Effect of acute and chronic administration of the aqueous extract of Lawsonia inermis leaves on haloperidol induced catalepsy in albino mice. Shastry C.S., Kiran U.P., Aswathanarayana BJ. Res J Pharm Biol Che Sci 2012;3(3):1107-16. 012;5(4):2355-65 Evaluation of Antivenom Activity of Calotropis Gigantea Plant Extract Against Vipera Russelli Snake Venom. Nimmy Chacko*, Mohammed Ibrahim, Prerana Shetty and C.S. Shastry, IJPSR (2012), Vol. 3, Issue 07 pp.2272-79 Hepatportective Activity Of Elettaria Cardamomum Against Paracetamol Induced Hepatoprotective Activity. Nimmy Chacko*, Ambily Thomas, C S Shastry, Prerana Shetty, Int J Pharm Pharm Sci, Vol 4, Issue 3, 611-613. Investigation of Investigation of pH dependant in situ gel forming solutions of imidazoline drug for ocular administration, Nisha G. Shetty*, Charyulu RN, Marina K, C. S Shastry, International Journal of Research in Pharmaceutical Sciences, 3(1), 120-126 2012, 1-7. Biochemical Studies on hepato and nephro protective effect of butter fly tree ( Bauhinia purpurea Linn. ) against acetaminophen induced toxicity. T. Sivanagi Reddy*, K.Prasanna Shama, P.Nirmala, C.S.Shastry. IJRAP 2012: 3(3). P.455-60. Anticholesteremic and Antilipidemic activity of Stem bark extracts of Moringa oleifera in Diet induced hyperlipidemia model in rats. Chitresh Senecha*, Prasanna Shama K, Ullas Prakash D’Souza, CS. Shastry. Int J Pharm Chem Scis 2012;1(3):567-74. Anti inflammatory and anti nociceptive evaluation of roots extracts of Bauhinia purpurea linn. Nirmala Jane Pais*, Ullas Prakash D Souza, Prasanna Shama K, Shastry CS. IJPCBS 2012;2(3):225-35. Comparative evaluation of diabetogenic and mutagenic potential of artificial sweeteners - aspartame, acesulfame-k and sucralose. Shastry C.S., Yatheesh C.K., Aswathanarayana B.J. NUJHS 2012;2(3):80-4. SIIC System of Assisted Editing (SSEA) / Sistema SIIC de Edición Asistida (SSEA)
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Information about the full text Acerca del trabajo completo Effect of Combination of Aripiprazole With Carbamazepine and Fluvoxamine on Liver Functions in Experimental Animals Author / Autor Chakrakodi Shastry1 1 S, Ngsm Institute Of Pharmaceutical Sciences Paneer, Deralakatte, Mangalore-575018, Mangalore, India, Principal Access to the original source Indian Journal of Pharmacology Article URL: / URL del artículo: http://www.ijp-online.com/ URL of Abstract page in Medline: / URL del abstract en Medline: http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23716885/ siic DB: / siic DB: http://www.siicsalud.com/main/distriprinrel.php |
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