OBESIDAD Y MORTALIDAD EN HOMBRES SEGUN EL ESTADO DE SU ENFERMEDAD CORONARIA

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Este estudio confirmó hallazgos anteriores de un aumento del riesgo de mortalidad por todas las causas, de enfermedad cardiovascular y de mortalidad por enfermedad coronaria en hombres independientemente de que padecieran o no enfermedad coronaria. Los hombres de edad media deben evitar el sobrepeso y la obesidad.
batty9.jpg Autor:
G. David batty
Columnista Experto de SIIC

Institución:
University of Glasgow


Artículos publicados por G. David batty
Coautores
George Davey Smith* João G Alves** Michael G. Marmot*** Martin J. Shipley**** 
MD, University of Bristol, Bristol, Reino Unido*
MD, Instituto Materno Infantil de Pernambuco, Recife, Brasil**
FRCP, University College London, Londres, Reino Unido***
MSc, University College London, Londres, Reino Unido****
Recepción del artículo
10 de Mayo, 2007
Aprobación
19 de Junio, 2007
Primera edición
8 de Febrero, 2008
Segunda edición, ampliada y corregida
7 de Junio, 2021

Resumen
Las pocas comunicaciones sobre la asociación de obesidad o sobrepeso con mortalidad en personas con enfermedad coronaria (EC) muestran hallazgos contradictorios. En el estudio Whitehall -en el que participaron empleados gubernamentales de sexo masculino de Londres-, 18 403 hombres de mediana edad que habían participado en un examen médico entre 1967 y 1970 fueron controlados durante 38 años. En los hombres que presentaban EC al inicio hubo pruebas de un riesgo ligeramente mayor de mortalidad por todas las causas y por EC, pero no por accidente cerebrovascular en los grupos con sobrepeso y obesidad en relación con los hombres de peso normal. Aunque estas tendencias fueron mucho más notables en los hombres sin EC al inicio del estudio, la diferencia según el estado basal de EC no alcanzó significación estadística en los niveles convencionales. Evitar la obesidad y el sobrepeso en la vida adulta tanto en hombres con EC como sin ella puede reducir el riesgo posterior de mortalidad total y mortalidad por cardiopatía coronaria.

Palabras clave
obesidad, sobrepeso, enfermedad coronaria, mortalidad


Artículo completo

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Abstract
The few reports on the association of obesity or overweight with mortality in persons with existing coronary heart disease (CHD) reveal inconsistent findings. In the Whitehall study of London-based male government employees, 18 403 middle-age men were followed up for up for a maximum of 38 years having participated in a medical examination between 1967 and 1970. In men with baseline CHD, there was evidence of a modest elevated risk for mortality from all-causes and coronary heart disease but not stroke in overweight and obese groups relative to normal weight men. While these slopes were markedly steeper in men who were CHD-free at study induction, the difference in the gradients according to baseline CHD status did not attain statistical significance at conventional levels. Avoidance of obesity and overweight in adult life in both men with and without CHD may reduce their later risk of total and coronary heart disease mortality.

Key words
obesity, overweight, coronary heart disease, mortality


Full text
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Clasificación en siicsalud
Artículos originales > Expertos del Mundo >
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Especialidades
Principal: Cardiología
Relacionadas: Endocrinología y Metabolismo, Epidemiología, Medicina Interna, Nutrición



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Enviar correspondencia a:
G. David Batty, University of Glasgow MRC Social & Public Health Sciences Unit, G12 8RZ, 4 Lilybank Gardens, Glasgow, Reino Unido
Patrocinio y reconocimiento:
Patrocinio: El examen de selección original de los participantes en el estudio Whitehall recibió fondos del Department of Health and Social Security y del Tobacco Research Council. Martin Shippley recibe una subvención de la British Heart Foundation; Michael Marmot recibe fondos del UK Medical Research Council; David Batty tiene una beca Wellcome Trust Fellowship. Agradecimiento: A los empleados públicos que brindaron su tiempo para tomar parte en este estudio.
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