Liane De Castro *

Autora invitada por SIIC

PREDIZENDO A HEPATOTOXICIDADE EM PACIENTES SUBMETIDOS AO TRATAMENTO PARA TUBERCULOSE.

A utilização do nomograma, para estimar a probabilidade de sobrevivência e o tempo mediano até a ocorrência de hepatotoxicidade, pode ser relevante para adequação da conduta terapêutica no tratamento da tuberculose. Essa adequação está diretamente relacionada ao sucesso do tratamento, e visa contribuir com as ações de controle da tuberculose.

*Liane De Castro
describe para SIIC los aspectos relevantes de su trabajo
CAN HEPATITIS B VIRUS INFECTION PREDICT TUBERCULOSIS TREATMENT LIVER TOXICITY? DEVELOPMENT OF A PRELIMINARY PREDICTION RULE
Institución principal de la investigación
*Fundação Oswaldo Cruz, Rio De Janeiro, Brasil
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Referencias bibliográficas
Tovo CV, Dos Santos DE, De Mattos AZ, et al. Ambulatorial prevalence of hepatitis B and C markers in patients with human immunodeficiency virus infection in a general hospital. Arq Gastroenterol 43(2):73-6.
Wong WM, Wu PC, Yuen MF, et al. Antituberculosis drug-related liver dysfunction in chronic hepatitis B infection. Hepatology 31(1):201-206, 2000.
Pan L, Jia Z, Chen L, Fu E, Li G. Effect of anti-tuberculosis therapy on liver function of pulmonary tuberculosis patients infected with hepatitis B virus. World J Gastroenterol 11(16):2518-2521, 2005.
Hoffmann CJ, Charalambous S, Thio CL, et al. Hepatotoxicity in an African antiretroviral therapy cohort: the effect of tuberculosis and hepatitis B. AIDS 21(10):1301-1308, 2007.
Sulkowski MS, Thomas DL, Mehta SH, Chaisson RE, Moore RD. Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections. Hepatology 35(1):182-189, 2002.
Zago AM, Machado TF, Cazarim FL, Miranda AE. Prevalence and risk factors for chronic hepatitis B in HIV patients attended at a sexually-transmitted disease clinic in Vitória, Brazil. Braz J Infect Dis 11(5):475-8, 2007.
Blal CA, Passos SRL, Horn C, et al. High prevalence of hepatitis B virus infection among tuberculosis patients with and without HIV in Rio de Janeiro, Brazil. European Journal of Clinical Microbiology & Infectious Diseases 24(1):41-43, 2005.

Otros artículos de Liane De Castro

Blal CA, Passos SRL, Horn C, et al. High prevalence of hepatitis B virus infection among tuberculosis patients with and without HIV in Rio de Janeiro, Brazil. European Journal of Clinical Microbiology & Infectious Diseases 24(1):41-43, 2005.
Gomes SA, De Castro L, Niel C, Santos EA. Uncommon mutation pattern of a hepatitis B virus isolate from genotype F infecting a patient with AIDS. Journal of Infection 48:102-108, 2004.
Lewisximenez LL, Oliveira JM, Mercadante LAC, De Castro L, Catarina WS, Stuver S, Yoshida CFT. Serological and Vaccination profile of hemodialysis patients during an outbreak of hepatitis B virus infection. Nephron 87:19-26, 2001.
De Castro L, Niel C, Gomes SA. Low frequency of mutations in the core promoter and precore regions of hepatitis B virus in anti-HBe positive Brazilian carriers. BMC Microbiology 1(10), 2001.
De Castro L, Araújo NM, Sabino RR, Alvarenga F, Yoshida CFT, Gomes SA. Nosocomial spread of hepatitis B in two hemodialysis units, investigate by restriction fragment length polymorphism analysis. European Journal Clinical Microbiology Infect Diseases 19:531-537, 2000.

Para comunicarse con Liane De Castro mencionar a SIIC como referencia:
liane.castro@ipec.fiocruz.br

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Acerca del trabajo completo

PREDIZENDO A HEPATOTOXICIDADE EM PACIENTES SUBMETIDOS AO TRATAMENTO PARA TUBERCULOSE.

Título original en castellano
A INFECÇÃO PELO VIRUS DA HEPATITE B PODE PREDIZER A TOXICIDADE HEPATICA NO TRATAMENTO DA TUBERCULOSE? DESENVOLVIMENTO DE UMA REGRA PRELIMINAR DE PREDIÇÃO.

Autores
Liane De Castro¹, Pedro Emmanuel Do Brasil², Thaís Pereira Monteiro³, Valéria Cavalcante Rolla⁴
1 Bióloga, Fundação Oswaldo Cruz, Rio De Janeiro, Brasil, Tecnologista
2 Médico, Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz, Tecnologista
3 Bióloga, Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz, Estudante de Mestrado Em Pesquisa Clínic
4 Médica, Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz, Tecnologista

Acceso a la fuente original
International Journal of Tuberculosis and Lung Disease
https://www.theunion.org/what-we-do/journals

ua40317