Maria Dalva Barbosa Baker Méio *

Autora invitada por SIIC

Foi utilizado o pareamento por idade gestacional e sexo para a comparação dos níveis séricos de IGF-1 e IGFBP-3 entre recém-nascidos com e sem restrição de crescimento intra-uterino.

IGFBP-3 COMO MARCADOR POTENCIAL DE RESTRIÇÃO DE CRESCIMENTO INTRA-UTERINO

Não houve diferença significativa nos níveis de IGF-1 entre recém-nascidos pequenos (PIG) e adequados (AIG) para idade gestacional no primeiro dia de vida, porém o IGFBP-3 encontrava-se significativamente reduzido nos recém-nascidos PIG. Concluiu-se que o IGFBP-3 é um marcador potencial de restrição de crescimento intra-uterino.

*Maria Dalva Barbosa Baker Méio
describe para SIIC los aspectos relevantes de su trabajo
REDUCTION OF IGF-BINDING PROTEIN-3 AS A POTENTIAL MARKER OF INTRA-UTERINE GROWTH RESTRICTION
Institución principal de la investigación
*Fundação Oswaldo Cruz, Río de Janeiro, Brasil
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Referencias bibliográficas
1. Albertsson-Wikland K, Boguszewski M, Karlberg J. Children born small-for-gestational age: postnatal growth and hormonal status. Horm Res 49(Suppl.2):7-13, 1998.
2. Barrios V, Argente J, Pozo J, Hervás F, Muñoz MT, Sánchez JI, et al. Insulin-like growth factor I, insulin-growth factor binding proteins, and growth hormone binding proteins in Spanish premature and full-term newborns. Horm Res 46:130-7, 1996.
3. Baxter RC. Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities. Am J Physiol Endocrinol Metab 278:E967-76, 2000.
4. Collet-Solberg PF, Cohen P. Genetics, chemistry, and function of the IGF/IGFBP system. Endocrine 12:121-36, 2000.
5. Conover CA, Bale LK, Durham SK, Powell DR. Insulin-like growth factor (IGF) binding protein-3 potentiation of IGF action is mediated through the phosphatidylinositol-3-kinase pathway and is associated with alteration in protein kinase B/AKT sensitivity. Endocrinology 141:3098-103, 2000.
6. Cutfield WS, Regan FA, Jackson WE, Jefferies CA, Robinson EM, Harris M, et al. The endocrine consequences for very low birth weight premature infants. Growth Horm IGF Res 14:S130-5, 2004.
7. Geary MPP, Pringle PJ, Rodeck CH, Kingdom JCP, Hindmarsh PC. Sexual dimorphism in the growth hormone and insulin-like growth factor axis at birth. J Clin Endocrinol Metab 88:3708-14, 2003.
8. Gluckman PD, Cutfield W. Harding JE, Milner D, Jensen E, Woodhall S, et al. Metabolic consequences of intra-uterine growth retardation. Acta Paediatr Suppl 417:3-6, 1996.
9. Golhke BC, Fahnenstich H, Dame C, Albers N. Longitudinal data for intrauterine levels of fetal IGF-I and IGF-II. Horm Res 61:200-4, 2004.
10. Giudice LC, de Zegher F, Garbosky SE, et al. Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J Clin Endocrinol Metab 80:1548-55, 1995.
11. Hofman PL, Cutfield WS, Robinson EM, Bergman RN, Menon RK, Sperling MA, et al. Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab 82:402-6, 1997.
12. Hofman PL, Regan F, Harris M, Robinson E, Jackson W, Cutfield WS. The metabolic consequences of prematurity. Growth Horm IGF Res 14:S136-9, 2004.
13. Hui-Chen L, Tsao LY, Hsu WY, Chen HN, Yu WK, Chi CY. Relation of cord serum levels of growth hormone, insulin-like growth factors, insulin-like growth factor binding proteins, leptin, and interleukin-6 with birth weight, birth length, and head circumference in term and preterm neonates. Nutrition 18:604-8, 2002.
14. Ibañez L, Ong K, Dunger DB, De Zegher F. Early development of adiposity and insulin resistance after catch up weight gain in small-for-gestational-age children. J Clin Endocrinol Metab 91:2153-8, 2006.
15. Juul A. Serum levels of insulin-like growth factor I and its binding proteins in health and disease. Growth Horm IGF Res 13:113-70, 2003.
16. Kramer MS, Platt RW, Wen SW, Joseph KS, Allen A, Abrahamowics M, et al. A new and improved population-based Canadian reference for birth weight for gestational age. Pediatrics 108:e35, 2001.
17. Langford K, Nicolaides K, Mielli JP. Maternal and fetal insulin-like growth factors and their binding proteins in the second and third trimesters of human pregnancy. Human Reproduction 13:1389-93, 1998.
18. Lassarre C, Hardouin S, Daffos F, FDorestier F, Frankenne F, Binoux M. Seruma insulin-like growth factors and insulin-like growth factor binding proteins in the human fetus. Relationship with growth in normal subjects and in subjects with intrauterine growth retardation. Pediatr Res 29:219-25, 1991.
19. Lee PA, Chermausek SD, Hokken-Koelega ACS, Czernichow P. International small for gestational age advisory board consensus development conference statement: management of short children born small for gestational age. Pediatrics 111:1253-61, 2003.
20. Leger J, Noel M, Limal JM, Czernichow P. Growth factors and intrauterine growth retardation. II. Serum growth hormone, insulin-like growth factor (IGF) I, and IGF-binding protein 3 levels in children with intrauterine retardation compared with nornmal controls subjects: prospective study from birth to two years of age. Pediatr Res 40:101-7, 1996.
21. Leger J, Levy-Marchal C, Bloch J, Pinet A, Chevenne D, Porquet D, et al. Reduced final height and indications for insulin resistance in 20 years old born small for gestational age: regional cohort study. Br Med J 315:341-7, 1997.
22. Lo HC, Tsao LY, Hsu WY, Chen HN, Yu WK, Chi CY. Relation of cord serum levels of growth hormone, insulin-like growth factor binding proteins, leptin. And interleukin-6 with birth weight, birth length, and head circumference in term and preterm neonates. Nutrition 18:604-8, 2002.
23. Malamitsi-Puchner A, Briana DD, Gourgiotis D, Boutsikou M, Puchner K-P, Baka S, et al. Insulin-like growth factor (IGF)-I and insulin in normal and growth restricted mother/infant pairs. Mediators Inflamm 2007:42646, 2007.
24. Mamelle N, Boniol M, Rivière O, Joly MO, Mellier G, Maria B, et al. Identification of newborns with fetal growth restriction (FGR) in weight and/or length based on constitutional growth potential. Eur J Pediatr 165:717-25, 2006.
25. Martínez Cordero C, Amador Licona A, Guízar Mendonza JM, Hernández Méndez J, Ruelas Orozco G. Body fat at birth and cord blood levels of insulin, adiponectin, leptin, and insulin growth factor I in small-for-gestational-age infants. Arch Med Res 37:490-4, 2006.
26. Modi N, Thomas EL, Harrington TAM, Uthaya S, Doré CJ, Bell DJ. Determinants of adiposity during pre-weaning postnatal growth in appropriately grown and growth-restricted term infants. Pediatr Res 60:345-8, 2006.
27. Mohan S, Baylink DJ. IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. J Endocrinol 175:19-31, 2002.
28. Singhal A, Fewtrell M, Cole TJ, Lucas A. Low nutrient intake and early growth for later insulin resistance in adolescents born preterm. Lancet 361:1089-97, 2003.
29. Vasrvarigou A, Vagenakis AG, Makri M, Beratis NG. Growth hormone, insulin-like growth factor-I and prolactin in small for gestational age neonates. Biology Neonate 65:94-102, 1994.
30. Verhaeghe J, Van Bree R, Van Herck E, laureys J, Bouillon R, Van Assche A, C-peptide, insulin-like growth factors I and II, and insulin-like growth factor binding protein-I in umbilical cord serum: correlations with brith weight. Am J Obstet Gynecol 169:89-97, 1993.
31. Verkauskiene R, Beltrand J, Claris O, Hevenne D, Deghmoun S, Dorgeret S, et al. Impact of fetal growth restriction on body composition and hormonal status at birth in infants of small and appropriate weight for gestational age. Eur J Endocrinol 157:605-12, 2007.
32. Wang HS, Lim J, English J, Irvine L, Chard T. The concentration of insulin-like growth factor-I and iunsulin-like growth factor binding protein-1 in human umbilical cord serum at delivery: relation to fetal weight. J Endocrinol 129:459-64, 1991.
33. Woods KA, Van Helvoirt M, Ong KKL, Mohn A, Levy J, de Zegher F, et al. The somatotropic axis in short children born small for gestational age: relation to insulin resistance. Pediatr Res 51:76-80, 2002.

Otros artículos de Maria Dalva Barbosa Baker Méio

Confiabilidade do teste WPPSI-R na avaliação do desenvolvimento cognitivo de pré-escolares. Cad Saúde Pública 17(1):99-105, 2001.
Fatores prognósticos para o desenvolvimento cognitivo de prematuros de muito baixo peso. Rev Saúde Pública 37(3):311-318,2003.
Desenvolvimento cognitivo de crianças prematuras de muito baixo peso na idade pré-escolar. Jornal de Pediatria (Rio J) 80(6):495-502,2004.
Total body water in small- and appropriate- for gestational age newborns J Perinat Med 36:354-358,2008.
Energy expenditure in very low birth weight newborns: a comparison between small and appropriate-for-gestational-age DOI:10.1111/j.1651-2227.2010.01686.x

Para comunicarse con Maria Dalva Barbosa Baker Méio mencionar a SIIC como referencia:
mdmeio@centroin.com.br

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Acerca del trabajo completo

IGFBP-3 COMO MARCADOR POTENCIAL DE RESTRIÇÃO DE CRESCIMENTO INTRA-UTERINO

Título original en castellano
REDUÇÃO DE IGFBP-3 COMO MARCADOR POTENCIAL DO CRESCIMENTO INTRA-UTERINO RESTRITO

Autores
Maria Dalva Barbosa Baker Méio¹, Maria Elizabeth Lopes Moreira², Rosely Sichieri³, Anibal Sánchez Moura⁴
1 Médica, Instituto Fernandes Figueira, Fundação Oswaldo Cruz, Río de Janeiro, Brasil, Medica
2 Médica, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, Neonatologista
3 Médica, Instituto de Medicina Social - Universidade Do Estado de Rio de Janeiro, Professora
4 Médico, Departamento de Ciências Fisiológicas - Uniersidade Do Estado Do Rio de Janeiro, Professor

Acceso a la fuente original
Journal of Perinatal Medicine
http://dx.doi.org/10.1515/jpm

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