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Chandra S.r
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CHOLINERGIC DYSFUNCTION IN MYASTHENIA GRAVIS- IS IT GENERALIZED?

Autonomic function testing was done in patients with myasthenia gravis in remission considering it as an index of generalized cholinergic dysfunction. In seropositive patients significant abnormality was found in frequency domain parameters and a trend was noted in duration domain parameters. There was also statistically significant decrease in time and frequency domain (RMSS and HFMD suggesting parasympathetic deficiency and change in low frequency/high frequency ratio suggesting increased sympathetic tone. This could be due to decrease in ACh signal processing at post ganglionic, preganglionic as well as smooth muscles of the heart. The impact on sympathetic is less because post ganglionic sympathetic synapses are much more than parasympathetic.

The article was published by
El artículo fue publicado por
Annals of Indian Academy of Neurology
Volume / Volumen: 16
Number / Número: 3
First and last pages / Páginas inicial-final: 329-332
Year / Año: 2013
Month / Mes: july


This journal, which is covered by SIIC Data Bases,
is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
Esta revista, clasificada por SIIC Data Bases,
integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.
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Principal institution where the research took place
Institución principal de la investigación
NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES, BANGALORE, KARNATAKA, India


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Bibliographic references
Referencias bibliográficas

Anderson NE, Hutchinson DO, Nicholson GJ, Aitcheson F, Nixon JM. Intestinal pseudo-obstruction, myasthenia gravis, and thymoma. Neurology 47:985-987, 1996.
Balestra B, Moretti M, Longhi R, Mantegazza R, Clementi F, Gotti C. Antibodies against neuronal nicotinic receptor subtypes in neurological disorders. J Neuroimmunol 102:89-97, 2000.
Rakocevic G, Barohn R, McVey AL, Damjanov I, Morte PD, Vernino S, et al. Myasthenia Gravis, Thymoma, and Intestinal Pseudo-Obstruction: A Case Report and Review. J Clin Neuromuscul Dis 5:93-95, 2003.
Tabbaa MA, Leshner RT, Campbell WW. Malignant thymoma with dysautonomia and disordered neuromuscular transmission. Arch Neurol 43:955-957, 1986.

Other articles written by the author Chandra S.r
Otros artículos de Chandra S.r





SIIC System of Assisted Editing (SSEA)
/ Sistema SIIC de Edición Asistida (SSEA)

Chandra S.r was invited by SIIC on
Chandra S.r fue invitado por SIIC el
2014, january 10
  The authors' report was accepted on
La crónica del autor fue aprobada el
2021, march 9
The authors' report was accepted on
La crónica del autor fue aprobada el
2021, march 9
Published in siicsalud
Publicado en siicsalud
2021, june 7





The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

 
Geriatrics
/ Geriatría
 
Neurology
/ Neurología
 

and secondarily related to the following sections

y secundariamente con las siguientes secciones

Inmunology
Inmunología

Internal Medicine
Medicina Interna

Information about the full text
Acerca del trabajo completo


Heart Rate and Blood Pressure Variability in Patients With Myasthenia Gravis


Author / Autor
Chandra S.r1, Puneeth Chikkulikere Sivan2, Chandran Sajish3, Yadav Ravi4, Sathyaprabha Talakad Narasappa5

5 Doctor, National Insttute Of Mental Health And Neurosciences; Bangalore-29, India, Professor


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Annals of Indian Academy of Neurology

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