EL HEXACLOROBENCENO COMO FACTOR DE RIESGO EN EL CANCER DE MAMA
Columnista Experta de SIIC Andrea S. Randi
en colaboración con
Kleiman de Pisarev Diana Leonor, Química, Universidad de Buenos Aires, Buenos Aires, Argentina; Alvarez Laura, Bióloga, Universidad de Buenos Aires, Buenos Aires, Argentina; Chiappini Florencia Ana, Bióloga, Universidad de Buenos Aires, Buenos Aires, Argentina; Zárate Lorena Vanesa, Estudiante, Universidad de Buenos Aires, Buenos Aires, Argentina; Ventura Clara, Biotecnóloga, Universidad de Buenos Aires, Buenos Aires, Argentina; Miret Noelia Victoria, Bióloga, Universidad de Buenos Aires, Buenos Aires, Argentina; Cocca Claudia Marcela, Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina; Pontillo Carolina Andrea, Bióloga, Universidad de Buenos Aires, Buenos Aires, Argentina
Fecha de aprobación: 9 de enero, 2018
Primera edición en siicsalud:
24 de enero, 2018
Sección Artículos originales,
subsección
Expertos de Iberoamérica,
página
/des/expertocompleto.php/153099
Especialidad principal:
Oncología
Toxicología
Especialidades relacionadas:
Bioquímica,Endocrinología y Metabolismo,Salud Ambiental,Salud Pública,
Andrea S Randi Hexachlorobenzene alters cell cycle by regulating p27-cyclin E-CDK2 and c-Src-p27 protein complexes, Toxicology Letters 270:72-79, 2017
Andrea S Randi Hexachlorobenzene modulates the crosstalk between the Aryl Hydrocarbon Receptor and Transforming Growth Factor %u03B21 signaling, enhancing human breast cancer cell migration and invasion, Toxicology 366:20-31, 2016
Andrea S Randi Enhanced cyclooxygenase-2 expression levels and metalloproteinase 2 and 9 activation by Hexachlorobenzene in human endometrial stromal cells, Biochemical Pharmacology 109:91-104, 2016
Andrea S Randi Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human microvascular endothelial cell line HMEC-1, Toxicology Letters 239:53-64, 2015
Andrea S Randi Chlorpyrifos inhibits cell proliferation through ERK1/2 phosphorylation in breast cancer cell lines, Chemosphere 120:343-350, 2015
Andrea S Randi Action of Hexachlorobenzene on tumor growth and metastasis in different experimental models, Toxicology and Applied Pharmacology 268:331-342, 2013
Andrea S Randi Alterations in c-Src/HER1 and Estrogen Receptor alpha signaling pathways in mammary gland and tumors of Hexachlorobenzene-treated rats, Toxicology 293:68-77, 2012
Andrea S Randi Activation of c-Src/ HER1/ STAT5b and HER1/ ERK1/2 signalling pathways and cell migration by hexachlorobenzene in MDA-MB-231 human breast cancer cell line, Toxicological Sciences 120:284-296, 2011
Andrea S Randi Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor %u03B1-dependent manner in MCF-7 breast cancer cell line, Toxicology Letters 192:195-205, 2010
Andrea S Randi Hexachlorobenzene is a tumor Co-carcinogen and induces alterations in Insulin Growth Factors Signaling Pathway in the Rat Mammary Gland, Toxicological Sciences 89:83-92, 2006
Andrea S Randi Hexachlorobenzene modulates the crosstalk between the Aryl Hydrocarbon Receptor and Transforming Growth Factor Beta1 signaling, enhancing human breast cancer cell migration and invasion, Toxicology 366:20-31, 2016
Andrea S Randi Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line, Toxicology Letters 192:195-205, 2010
Andrea S. Randi
Dirección profesional:
Paraguay 2155 - 1121, Buenos Aires, Argentina