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DIFERENCIAS SEGUN EL SEXO EN PACIENTES CON TRAUMATISMO DE CRANEO

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Los pacientes que han sufrido un traumatismo craneoencefálico parecen tener una alteración de la regulación cardíaca y al parecer existen algunas pruebas de diferencias según el sexo en los parámetros de variabilidad de la frecuencia cardíaca.
slewayounan9.jpg Autor:
Shameran Slewa-younan
Columnista Experto de SIIC
Artículos publicados por Shameran Slewa-younan
Coautores
Ian J. Baguley* Roxana E. Heriseanu** Ian D. Cameron*** 
MBBS, University of Sydney, Sydney, Australia*
MBBS, University of Bucharest, Bucarest, Rumania**
MBBS, PhD in Medicine, University of Sydney, Sydney, Australia***
Recepción del artículo
11 de Febrero, 2007 		Aprobación
16 de Marzo, 2007
Primera edición
9 de Agosto, 2007 		Segunda edición, ampliada y corregida
7 de Junio, 2021

DIFERENCIAS SEGUN EL SEXO EN PACIENTES CON TRAUMATISMO DE CRANEO

Resumen
Antecedentes: Se reconocen cada vez más diferencias según el sexo en el pronóstico luego del traumatismo craneoencefálico (TCE). Este artículo examina si dichas diferencias se observan en los valores de la variabilidad de la frecuencia cardíaca (VFC), medida de la cual se halló previamente que se correlacionaba con la gravedad de la lesión y su pronóstico. Materiales, métodos y resultados: Se obtuvieron datos de 16 sujetos que habían sufrido un TCE y de controles apareados por edad y sexo. Los datos incluyeron detalles del traumatismo, registro electrocardiográfico continuo y resultado de la rehabilitación. Se observaron pruebas de disfunción cardíaca en los datos del TCE comparados con sus controles sanos apareados. Además, hubo una sugerencia preliminar de diferencias según el sexo en los parámetros de la VFC del grupo con TCE. Conclusiones: Los hallazgos en este grupo concuerdan con la bibliografía sobre la VFC luego de un TCE. Es recomendable que este trabajo continúe con otros artículos en los que se realicen estudios con una muestra más grande de sujetos con TCE para examinar detalladamente las diferencias según el sexo en los parámetros de la VFC.

Palabras clave
lesión cerebral traumática, diferencias de sexo, variabilidad de la frecuencia cardíaca


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Sex Differences In Heart Rate Variability Following Acute Traumatic Brain Injury

Abstract
Background: Sex differences in outcome following traumatic brain injury (TBI) are becoming increasingly recognised. This paper examines whether such differences are found on measures of heart rate variability (HRV), a measure previously found to correlate with injury severity and outcome. Materials, methods and results: Data was collected on 16 subjects with TBI and their age and sex matched controls. Data included injury details, continuous electrocardiograph recordings and rehabilitation outcome. Evidence of cardiac dysfunction was found in the TBI data compared to their matched healthy controls. Furthermore, there was preliminary suggestion of sex differences in the HRV parameters of the TBI group. Conclusions: These group findings replicate previous literature on HRV following TBI. The need to follow-up this paper with larger sample of TBI subjects in order to thoroughly examine sex differences in HRV parameters is recommended.

Key words
traumatic brain injury, sex differences, heart rate variability


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Especialidades
Principal: Neurología
Relacionadas: Atención Primaria, Cardiología, Cuidados Intensivos, Emergentología, Medicina Interna, Ortopedia y Traumatología



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Enviar correspondencia a:
Shameran Slewa-Younan, Brain Injury Rehabilitation Service, Westmead Hospital , 2145 NSW, PO Box 533, Wentworthville, Australia
Patrocinio y reconocimiento:
Esta investigación fue financiada por un subsidio para investigaciones importantes de la NSW Motor Accidents Authority (MAA). Además, este estudio forma parte de la especialización posdoctoral de Shameran Slewa-Younan, quien recibió fondos del National Health and Medical Research Council (NHMRC) de Australia. Agradecemos al personal de investigación de la UCI que ayudó a recoger los datos, y también al personal del laboratorio de Endocrinología en ICPMR del Westmead Hospital por su asistencia con la determinación de las hormonas sexuales.
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