Alberto Camacho *

Autor invitado por SIIC

El trabajo determina el efecto de la ingesta de dieta hipercalórica en la aparición de daño cerebral a nivel de mitocondria y el retículo endoplásmico y su contribución en el desarrollo de diabetes.

INFLUENCIA DE LA OBESIDAD EN LA APARICIÓN DE DAÑO CEREBRAL A NIVEL MITOCONDRIAL

La ingesta de dietas hipercalóricas modula la comunicación y función mitocondrial y del retículo endoplásmico en el sistema nervioso.

*Alberto Camacho
describe para SIIC los aspectos relevantes de su trabajo
ROLES OF CALCIUM AND MITOCHONDRIA-ASSOCIATED MEMBRAES IN THE DEVELOPMENT OF OBESITY AND DIABETES
Institución principal de la investigación
*Universidad Autónoma de Nuevo León, Monterrey, México
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Referencias bibliográficas
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Otros artículos de Alberto Camacho

Torres Villarreal D, Camacho A, Milagro FI, Ortiz López R, De la Garza AL. Quercetin ameliorates inflammation in 3T3-L1 adipocytes and decreases intestinal sugar uptake in Caco-2 cells and rats. Natural Product Communications 2017. Aceptado. En prensa.
Maldonado Ruiz R, Fuentes Mera L, Camacho A. Central modulation of neuroinflammation by neuropeptides and energy-sensing hormones during obesity. BioMed Research International 7949528, 2017.
Camacho A, Montalvo L, Cárdenas Pérez RE, Fuentes Mera L, Garza Ocañas L. Obesogenic diet intake during pregnancy programs aberrant synaptic plasticity and addiction-like behavior to hipercaloric diet in offspring. Behavioural Brain Research 330:46-55, 2017.
Maldonado Ruiz R, Montalvo Martínez L, Fuentes Mera L, Camacho A. Microglia activation due to obesity programs metabolic failure leading to type two diabetes. Nutrition and Diabetes 7(3):e2542017, 2017.
Díaz B, Fuentes Mera L, Tovar A, Montiel T, Massieu L, Martínez Rodríguez HG, Camacho A. Saturated lipids decrease mitofusin 2 leading to endoplasmic reticulum stress activation and insulin resistance in hypothalamic cells. Brain Research 1627:80-9, 2015.
Delint Ramírez U, Maldonado Ruiz R, Torre Villalvazo I, Garza Ocañas L, Tovar A, Camacho A. Genetic obesity alters recruitment of TANK-binding kinase 1 and AKT into hypothalamic lipid rafts domains. Neurochemistry International 80:23-32, 2015.
Camacho A, Huang JK, Delint Ramírez I, Yew Tan C, Fuller M, Lelliott CJ, Vidal Puig A, Franklin RJ. Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis. Eur J Neurosci 38(5):2672-83, 2013.
Camacho A, Rodríguez-Cuenca S, Blount M, Prieur X, Barbarroja N, Hardingham GE, Vidal Puig A. Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response. Exp Neurol 237(2):396-406, 2012.
Prieur X, Velagapudi VR, Núñez V, Mok C, Fuentes L, Montaner D, Ishikawa K, Camacho A, O'Rahilly S, Sethi J, Dopazo J, Oresic M, Ricote M, Vidal Puig A. Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarisation in obese mice. Diabetes 60(3):797-809, 2011.

Para comunicarse con Alberto Camacho mencionar a SIIC como referencia:
acm590@hotmail.com

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Acerca del trabajo completo

INFLUENCIA DE LA OBESIDAD EN LA APARICIÓN DE DAÑO CEREBRAL A NIVEL MITOCONDRIAL

Título original en castellano
PAPEL DEL CALCIO Y DE LAS MEMBRANAS ASOCIADAS A LA MITOCONDRIA EN EL DESARROLLO DE OBESIDAD Y DIABETES

Autor
Robbi- E Cardenas Perez¹
1 Estudiante Doctorado, Universidad Autónoma de Nuevo León, Estuadiante

Acceso a la fuente original
Medicina Universitaria
http://www.uanl.mx/publicaciones/medicina-universitaria/

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