Antonio Correia *

Autor invitado por SIIC

BACTÉRIAS RESISTENTES A CARBAPENEMOS EM ÁGUAS DE RIOS

Há bactérias altamente resistentes a antibióticos em rios. A poluição das águas é um factor que contribui para o tipo de resistência: em águas poluídas surgem resistências típicas de ambientes hospitalares; em águas não poluídas as resistências são “primitivas”, baseiam-se nos naturais mecanismos de defesa das bactérias contra antagonistas.

*Antonio Correia
describe para SIIC los aspectos relevantes de su trabajo
RESISTANCE TO BROAD-SPECTRUM ANTIBIOTICS IN AQUATIC SYSTEMS: ANTHROPOGENIC ACTIVITIES MODULATE THE DISSEMINATION OF BLA(CTX-M)-LIKE GENES
Institución principal de la investigación
*Departamento de Biologia, Universidade de Aveiro, Aveiro, Portugal
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Referencias bibliográficas
Bibliografía
Henriques I, Araújo S, Azevedo JSN, Alves MS, Chouchani C, Pereira A, Correia A. Diversity of carbapenem-resistant bacteria in untreated drinking water. Microbial Drug Resistance, 2012, in press.
Chouchani C, Marrakchi R, Henriques I, Correia A. Occurrence of IMP-8, IMP-10 and IMP-13 metallo-B-lactamases located on class one integrons and other ESBLs in bacterial isolates from Tunisian rivers. Scandinavian Journal of Infectious Diseases, 2012, in press.
Moura A, Jové T, Ploy MC, Henriques I, Correia A. Diversity of gene cassette promoters in class 1 integrons from wastewater environments. Applied and Environmental Microbiology 78:5413-5416, 2012.
Tacão M, A. Correia, and I. Henriques. 2012. Has antibiotic resistance cracked the (lotic) system? - polluted vs unpolluted environmental resistome. Applied and Environmental Microbiology 78:4134–4140.
Moura A, Oliveira CS, Henriques I, Smalla K, Correia A. Broad diversity of conjugative plasmids in integron-carrying bacteria from wastewater environments. FEMS Microbiology Letters 330:157-164, 2012.
Oliveira CS, Lázaro B, Azevedo JSN, Henriques I, Almeida A, Correia A. New molecular variants of Epsilon and Beta IncP-1 plasmids are present in estuarine waters. Plasmid 67:252-258, 2012.
Moura A, Pereira C, Henriques I, Correia A. Novel gene cassettes and integrons in antibiotic resistant bacteria isolated from urban wastewaters. Research in Microbiology 163:92-100, 2012.
Fonseca F, Arthur CJ, Bromley E, Samyn B, Moerman P, Saavedra MJ, Correia A, Spencer J. Biochemical characterization of Sfh-I, the subclass B2 metallo-B-lactamase from Serratia fonticola UTAD54. Antimicrobial Agents and Chemotherapy 55:5392–5395, 2011.
Fonseca F, Bromley E, Saavedra M, Correia A, Spencer J. Crystal structure of Serratia fonticola Sfh-I: Activation of the nucleophile in the catalytic mechanism of mono-zinc metallo-B-lactamases. Journal of Molecular Biology 411:951-959, 2011.
Moura A, Henriques I, Smalla K, Correia A. Wastewater bacterial communities bring together broad-host range plasmids, integrons, and a large diversity of uncharacterized gene cassettes. Research in Microbiology 161:58-66, 2010.