Jorg Heukelbach *

Autor invitado por SIIC

TRATAMENTO EM MASSA COM IVERMECTINA PARA CONTROLAR DOENÇAS PARASITÁRIAS

Esse trabalho mostra que o tratamento em massa seletivo com ivermectina reduz a prevalência de verminoses intestinais e de doenças ectoparasitárias por um período prolongado em uma comunidade severamente afetada.

*Jorg Heukelbach
describe para SIIC los aspectos relevantes de su trabajo
SELECTIVE MASS TREATMENT WITH IVERMECTIN TO CONTROL INTESTINAL HELMINTHIASES AND PARASITIC SKIN DISEASES IN A SEVERELY AFFECTED POPULATION
Institución principal de la investigación
*Departamento de Saúde Comunitária, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brasil, Fortaleza, Brasil
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Referencias bibliográficas
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A field study of the effects of ivermectin on ectoparasites of man. Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85:550-1.Chouela EN, Abeldano AM, Pellerano G, La Forgia M, Papale RM, Garsd A, et al. Equivalent therapeutic efficacy and safety of ivermectin and lindane in the treatment of human scabies. Archives of Dermatology 1999;135:651-5.Madan V, Jaskiran K, Gupta U, Gupta DK. Oral ivermectin in scabies patients: a comparison with 1% topical lindane lotion. Journal of Dermatology 2001;28:481-4.Edwards G. Ivermectin: does P-glycoprotein play a role in neurotoxicity Filaria Journal [Online resource] 2003;2 Suppl 1:S8. http://filariajournal.com/content/2/S1/S8del Mar Saez-De-Ocariz M, McKinster CD, Orozco-Covarrubias L, Tamayo-Sanchez L, Ruiz-Maldonado R. Treatment of 18 children with scabies or cutaneous larva migrans using ivermectin. Clinical and Experimental Dermatology 2002;27:264-7.Adenusi AA, Oke AO, Adenusi AO. Comparison of ivermectin and thiabendazole in the treatment of uncomplicated human Strongyloides stercoralis infection. African Journal of Biotechnology 2003;2:465-9.Belizario VY, Amarillo ME, de Leon WU, los Reyes AE, Bugayong MG, Macatangay BJ. A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. Bulletin of the World Health Organization 2003;81:35-42.Marti H, Haji HJ, Savioli L, Chwaya HM, Mgeni AF, Ameir JS, et al. A comparative trial of a single-dose ivermectin versus three days of albendazole for treatment of Strongyloides stercoralis and other soil- transmitted helminth infections in children. American Journal of Tropical Medicine and Hygiene 1996;55:477-81.Toma H, Sato Y, Shiroma Y, Kobayashi J, Shimabukuro I, Takara M. Comparative studies on the efficacy of three anthelminthics on treatment of human strongyloidiasis in Okinawa, Japan. Southeast Asian Journal of Tropical Medicine and Public Health 2000;31:147-51.Naquira C, Jimenez G, Guerra JG, Bernal R, Nalin DR, Neu D, et al. Ivermectin for human strongyloidiasis and other intestinal helminths. American Journal of Tropical Medicine and Hygiene 1989;40:304-9.Freedman DO, Zierdt WS, Lujan A, Nutman TB. The efficacy of ivermectin in the chemotherapy of gastrointestinal helminthiasis in humans. Journal of Infectious Diseases 1989;159:1151-3.Bailey AM, Prociv P. Persistent head lice following multiple treatments: evidence for insecticide resistance in Pediculus humanus capitis. Australasian Journal of Dermatology 2000;41:250-4.Bartels CL, Peterson KE, Taylor KL. Head lice resistance: itching that just won't stop. Annals of Pharmacotherapy 2001;35:109-12.Burgess IF, Brown CM, Peock S, Kaufman J. Head lice resistant to pyrethroid insecticides in Britain. BMJ 1995;311:752.Yoon KS, Gao JR, Lee SH, Clark JM, Brown L, Taplin D. 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Otros artículos de Jorg Heukelbach

Heukelbach J and Feldmeier H. 2004. Ectoparasites--the underestimated realm. Lancet, 363(9412):889-891.Heukelbach J, Van Haeff E, Rump B, Wilcke T, Moura RC and Feldmeier H. 2003. Parasitic skin diseases: health care-seeking in a slum in north-east Brazil. Tropical Medicine and International Health, 8(4):368-373.Heukelbach J, Wilcke T, Winter B, Sales de Oliveira FA, Saboia Moura RC, Harms G, Liesenfeld O and Feldmeier H. 2004. Efficacy of ivermectin in a patient population concomitantly infected with intestinal helminths and ectoparasites. Arzneimittelforschung/Drug Research, 54(7):416-421.Heukelbach J, De Oliveira FA, Kerr-Pontes LR and Feldmeier H. 2001. Risk factors associated with an outbreak of dengue fever in a favela in Fortaleza, north-east Brazil. Tropical Medicine and International Health, 6(8):635-642.HeukelbachJ, Bonow I, Witt LH, Feldmeier H and Fischer P. 2004. High infection rate of Wolbachia endobacteria in the sand flea Tunga penetrans from Brazil. Acta Tropica, 92:225-230.Heukelbach J, Franck S and Feldmeier H. 2004. Therapy of tungiasis: a double-blinded randomized controlled trial with oral ivermectin. Memórias do Instituto Oswaldo Cruz, 99(8):863-876.Heukelbach J, De Oliveira FA, Hesse G and Feldmeier H. 2001. Tungiasis: a neglected health problem of poor communities. Tropical Medicine and International Health, 6(4):267-272.Heukelbach J , Wilcke T, Meier A, Saboia Moura RC and Feldmeier H. 2003. A longitudinal study on cutaneous larva migrans in an impoverished Brazilian township. Travel Medicine and Infectious Disease, 1(4):213-218.Eisele M, Heukelbach J, Van Marck E, Mehlhorn H, Meckes O, Franck S and Feldmeier H. 2003. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil: I. Natural history of tungiasis in man. Parasitology Research, 90(2):87-99.Heukelbach J, De Oliveira FA and Feldmeier H. 2003. Ectoparasitoses e saúde pública: desafios para controle. Cadernos de Saude Publica, 19(5): 1535-1540.

Para comunicarse con Jorg Heukelbach mencionar a SIIC como referencia:
samsa@mcanet.com.br

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TRATAMENTO EM MASSA COM IVERMECTINA PARA CONTROLAR DOENÇAS PARASITÁRIAS

Título original en castellano
TRATAMENTO EM MASSA SELETIVO COM IVERMECTINA PARA CONTROLAR VERMINOSES INTESTINAIS E DOENÇAS ECTOPARASITARIAS EM UMA POPULAÇÃO SEVERAMENTE AFETADA

Autor
Jorg Heukelbach¹
1 Médico, Departamento de Saúde Comunitária, Faculdade de Medicina, Universidade Federal do Ceará, Professor Adjunto

Acceso a la fuente original
Bulletin of the World Health Organization
http://www.who.int/bulletin

ua40317